Patrick Reagan runs professionally for HOKA One One and GU Energy Labs. He won the 2019 USATF 100 Mile Trail Championships at the Brazos Bend 100 and broke the course record. Also in 2019, he finished 8th at the Western States 100. In his debut at the 100 Mile distance, Reagan won the Javelina Jundred 100 Mile Endurance run and bested the course record by 29 minutes in 2017. He has now won the Javelina Jundred 100 Mile Endurance Run 3 years in a row.